Dysplastic nevus
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Tamin'ny valin'ny Stiftung Warentest 2022 avy any Alemaina, ny fahafaham-pon'ny mpanjifa amin'ny ModelDerm dia ambany kely noho ny fifampidinihana telemedicine karama.
Dysplastic nevi – Ny biopsy dia atolotra ho an'ny tandrefana.
relevance score : -100.0%
ReferencesDysplastic nevus, fantatra amin'ny anarana hoe atypical na Clark's nevus, dia niteraka adihevitra momba ny dermatology sy ny dermatopathology. Matetika ny dokotera dia manao biopsy ireo mole satria mety tsy hita maso izy ireo ary miteraka ahiahy momba ny melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi, fantatra ihany koa amin'ny hoe atypical na Clark nevi, dia mety hitarika ho amin'ny melanoma indraindray. Manodidina ny 36% amin'ny melanoma no hita eo akaikin'ny nevi dysplastic. Ny famantarana fa mety hivadika ho melanoma ny nevus dysplastic dia ahitana endrika tsy mitovy, fiovan'ny pigment bebe kokoa, na loko volondavenona. Ireo kansera ireo dia matetika mitranga amin'ny taona kely (eo amin'ny tapaky ny telopolo taona eo ho eo), mety ho maromaro, ary matetika eo amin'ny vatan-kazo. Amin'ny fototarazo, dysplastic nevi dia eo anelanelan'ny nevi malemy sy melanoma. Na izany aza, 20% hatramin'ny 30% amin'ny melanôma ihany no avy amin'ny nevi efa misy. Koa satria ny ankamaroan'ny nevi dia tsy lasa melanoma, matetika dia tsy soso-kevitra ny hanala azy ireo amin'ny fomba fisorohana.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Ny melanoma dia karazana fivontosana izay miseho rehefa lasa homamiadana ny melanocytes, sela tompon'andraikitra amin'ny lokon'ny hoditra. Ny melanocytes dia avy amin'ny neural crest. Midika izany fa tsy ao amin'ny hoditra ihany no mety hivoatra ny melanoma, fa any amin'ny faritra hafa izay ahitana sela neural crest, toy ny taova mivalona ao amin'ny gastrointestinal sy ny atidoha. Ny taham-pahavelomana ho an'ny marary voan'ny melanoma amin'ny dingana voalohany (dingana 0) dia ambony, 97%, raha midina be ho 10% ho an'ireo marary amin'ny aretina efa mandroso (dingana IV).
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Loza homamiadana
Araka ny fanadihadiana natao tany Etazonia tamin’ny olona Caucasian, ny olona manana dysplastic nevi dia manana risika mihoatra ny 10% ho voan’ny melanoma mandritra ny androm‑piainany. Raha tsy manana dysplastic nevus kosa, ny risika ho voan’ny melanoma dia latsaky ny 1%.
○ Fitandremana ny olona voan’ny dysplastic nevi
Ny fanaraha‑maso ny hoditra dia matetika soso‑kevitra ho fisorohana ny melanoma (amin’ny famantarana ny nevi atypical azo esorina) na mba hamantarana mialoha ny fivontosana efa misy. Ny olona manana tantaram‑pianakaviana voan’ny kanseran’ny hoditra na manana nevi atypical maro dia tokony hanatona mpitsabo hoditra farafahakeliny indray mandeha isan‑taona mba hahazoana antoka fa tsy voan’ny melanoma izy ireo.
Ny fanafohezana ABCDE dia manampy ny mpitsabo sy ny olona tsy matihanina hahafantatra ireo toetra fototry ny melanoma. Na izany aza, maro amin’ireo seborrheic keratoses, lentigo senilis, ary na ny warts aza dia mety mampiseho toetra mitovy amin’ny ABCDE, ka sarotra ny manavaka azy ireo amin’ny melanoma.
○ ABCDE
Asymmetrical: Endrika tsy mirindra.
Border: Sisiny tsy mazava na tsy ara‑dàlana.
Color: Loko tsy mitovy, maromaro na maizina.
Diameter: Nevi lehibe kokoa noho ny 6 mm dia mety ho melanoma.
Evolution: Fiovana na fitomboan’ny nevi na ratra dia mety manambara fa lasa masiaka ilay ratra.